STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACI17842.1Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology. (332 aa)    
Predicted Functional Partners:
rplI
50S ribosomal protein L9; Binds to the 23S rRNA.
       0.773
dnaB
DNA helicase; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity. Belongs to the helicase family. DnaB subfamily.
 
     0.739
leuS
leucine--tRNA ligase; LeuRS; class-I aminoacyl-tRNA synthetase; charges leucine by linking carboxyl group to alpha-phosphate of ATP and then transfers aminoacyl-adenylate to its tRNA; due to the large number of codons that tRNA(Leu) recognizes, the leucyl-tRNA synthetase does not recognize the anticodon loop of the tRNA, but instead recognition is dependent on a conserved discriminator base A37 and a long arm; an editing domain hydrolyzes misformed products; in Methanothermobacter thermautotrophicus this enzyme associates with prolyl-tRNA synthetase; Derived by automated computational [...]
       0.705
ACI17262.1
Competence protein ComEA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.705
ACI17966.1
Competence protein ComEC; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.705
rpsR
30S ribosomal protein S18; Binds as a heterodimer with protein S6 to the central domain of the 16S rRNA, where it helps stabilize the platform of the 30S subunit; Belongs to the bacterial ribosomal protein bS18 family.
       0.489
ACI17901.1
PBP 5 synthesis repressor; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.484
ACI17431.1
Thiamine transporter; Derived by automated computational analysis using gene prediction method: Protein Homology.
  
     0.451
ACI17356.2
Hypothetical protein; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.432
gyrB
DNA gyrase subunit B; Negatively supercoils closed circular double-stranded DNA; Derived by automated computational analysis using gene prediction method: Protein Homology.
       0.432
Your Current Organism:
Coprothermobacter proteolyticus
NCBI taxonomy Id: 309798
Other names: C. proteolyticus DSM 5265, Coprothermobacter proteolyticus DSM 5265
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