STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source. (540 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.944
nadE-2
NH(3)-dependent NAD(+) synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
0.943
nadK
Probable inorganic polyphosphate/ATP-NAD kinase (Poly(P)/ATP NAD kinase); Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.941
ACI19302.1
Glutamate synthase domain 3; Identified by match to protein family HMM PF01493.
       0.723
guaA
GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP.
   
 
 0.717
ACI18605.1
Competence-damage inducible protein; Identified by match to protein family HMM PF00994; match to protein family HMM PF02464; match to protein family HMM TIGR00177; match to protein family HMM TIGR00199; match to protein family HMM TIGR00200; Belongs to the CinA family.
  
  
 0.713
ACI18462.1
Glutamate synthase; Identified by match to protein family HMM PF00037; match to protein family HMM PF01645; Belongs to the glutamate synthase family.
     
 0.709
ACI18766.1
Glutamate synthase domain 1; Identified by match to protein family HMM PF00310.
       0.700
ACI19197.1
NADH oxidase; Identified by match to protein family HMM PF00070; match to protein family HMM PF07992.
       0.693
ACI19479.1
Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037.
       0.651
Your Current Organism:
Dictyoglomus thermophilum
NCBI taxonomy Id: 309799
Other names: D. thermophilum H-6-12, Dictyoglomus thermophilum H-6-12
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