node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACI18355.1 | ACI18515.1 | DICTH_0334 | DICTH_0336 | Phosphoribosylformylglycinamidine cyclo-ligase. | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | 0.956 |
ACI18355.1 | ACI18831.1 | DICTH_0334 | DICTH_1553 | Phosphoribosylformylglycinamidine cyclo-ligase. | ThiC family; Identified by match to protein family HMM PF01964. | 0.802 |
ACI18355.1 | ACI18843.1 | DICTH_0334 | DICTH_0335 | Phosphoribosylformylglycinamidine cyclo-ligase. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.956 |
ACI18355.1 | ACI19678.1 | DICTH_0334 | DICTH_0333 | Phosphoribosylformylglycinamidine cyclo-ligase. | Hypothetical protein; Identified by glimmer; putative. | 0.773 |
ACI18355.1 | guaB | DICTH_0334 | DICTH_0584 | Phosphoribosylformylglycinamidine cyclo-ligase. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.680 |
ACI18355.1 | purB | DICTH_0334 | DICTH_1317 | Phosphoribosylformylglycinamidine cyclo-ligase. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.694 |
ACI18355.1 | purL | DICTH_0334 | DICTH_1314 | Phosphoribosylformylglycinamidine cyclo-ligase. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.965 |
ACI18355.1 | purM | DICTH_0334 | DICTH_1312 | Phosphoribosylformylglycinamidine cyclo-ligase. | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. | 0.900 |
ACI18355.1 | purQ | DICTH_0334 | DICTH_1315 | Phosphoribosylformylglycinamidine cyclo-ligase. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.965 |
ACI18355.1 | purS | DICTH_0334 | DICTH_1316 | Phosphoribosylformylglycinamidine cyclo-ligase. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.968 |
ACI18515.1 | ACI18355.1 | DICTH_0336 | DICTH_0334 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.956 |
ACI18515.1 | ACI18831.1 | DICTH_0336 | DICTH_1553 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | ThiC family; Identified by match to protein family HMM PF01964. | 0.802 |
ACI18515.1 | ACI18843.1 | DICTH_0336 | DICTH_0335 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | Phosphoribosylformylglycinamidine cyclo-ligase. | 0.996 |
ACI18515.1 | ACI19678.1 | DICTH_0336 | DICTH_0333 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | Hypothetical protein; Identified by glimmer; putative. | 0.580 |
ACI18515.1 | guaB | DICTH_0336 | DICTH_0584 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.680 |
ACI18515.1 | purB | DICTH_0336 | DICTH_1317 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | Adenylosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00928; Belongs to the lyase 1 family. Adenylosuccinate lyase subfamily. | 0.694 |
ACI18515.1 | purL | DICTH_0336 | DICTH_1314 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | Phosphoribosylformylglycinamidine synthase II; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist [...] | 0.971 |
ACI18515.1 | purM | DICTH_0336 | DICTH_1312 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR00878. | 0.913 |
ACI18515.1 | purQ | DICTH_0336 | DICTH_1315 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | Phosphoribosylformylglycinamidine synthase I; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought to assist i [...] | 0.973 |
ACI18515.1 | purS | DICTH_0336 | DICTH_1316 | Phosphoribosylformylglycinamidine cyclo-ligase; Identified by match to protein family HMM PF02769. | Phosphoribosylformylglycinamidine synthase, PurS protein; Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is thought [...] | 0.968 |