node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACI18448.1 | ACI18717.1 | DICTH_1158 | DICTH_1161 | Thiamine pyrophosphokinase; Identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378. | Identified by match to protein family HMM PF06071. | 0.588 |
ACI18448.1 | ACI19019.1 | DICTH_1158 | DICTH_1160 | Thiamine pyrophosphokinase; Identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378. | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.561 |
ACI18448.1 | ACI20058.1 | DICTH_1158 | DICTH_1157 | Thiamine pyrophosphokinase; Identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378. | Thiamine transporter. | 0.813 |
ACI18448.1 | gyrA | DICTH_1158 | DICTH_1159 | Thiamine pyrophosphokinase; Identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.602 |
ACI18717.1 | ACI18448.1 | DICTH_1161 | DICTH_1158 | Identified by match to protein family HMM PF06071. | Thiamine pyrophosphokinase; Identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378. | 0.588 |
ACI18717.1 | ACI19019.1 | DICTH_1161 | DICTH_1160 | Identified by match to protein family HMM PF06071. | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.780 |
ACI18717.1 | ACI20058.1 | DICTH_1161 | DICTH_1157 | Identified by match to protein family HMM PF06071. | Thiamine transporter. | 0.562 |
ACI18717.1 | gyrA | DICTH_1161 | DICTH_1159 | Identified by match to protein family HMM PF06071. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.845 |
ACI19019.1 | ACI18448.1 | DICTH_1160 | DICTH_1158 | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Thiamine pyrophosphokinase; Identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378. | 0.561 |
ACI19019.1 | ACI18717.1 | DICTH_1160 | DICTH_1161 | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Identified by match to protein family HMM PF06071. | 0.780 |
ACI19019.1 | ACI19598.1 | DICTH_1160 | DICTH_1452 | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Hypothetical protein; Identified by glimmer; putative. | 0.702 |
ACI19019.1 | ACI20058.1 | DICTH_1160 | DICTH_1157 | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | Thiamine transporter. | 0.561 |
ACI19019.1 | gyrA | DICTH_1160 | DICTH_1159 | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.797 |
ACI19019.1 | rtcB | DICTH_1160 | DICTH_1853 | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | RtcB protein; Identified by match to protein family HMM PF01139; Belongs to the RtcB family. | 0.939 |
ACI19598.1 | ACI19019.1 | DICTH_1452 | DICTH_1160 | Hypothetical protein; Identified by glimmer; putative. | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.702 |
ACI19598.1 | rtcB | DICTH_1452 | DICTH_1853 | Hypothetical protein; Identified by glimmer; putative. | RtcB protein; Identified by match to protein family HMM PF01139; Belongs to the RtcB family. | 0.608 |
ACI20058.1 | ACI18448.1 | DICTH_1157 | DICTH_1158 | Thiamine transporter. | Thiamine pyrophosphokinase; Identified by match to protein family HMM PF04263; match to protein family HMM TIGR01378. | 0.813 |
ACI20058.1 | ACI18717.1 | DICTH_1157 | DICTH_1161 | Thiamine transporter. | Identified by match to protein family HMM PF06071. | 0.562 |
ACI20058.1 | ACI19019.1 | DICTH_1157 | DICTH_1160 | Thiamine transporter. | Conserved hypothetical protein; Activates the tRNA-splicing ligase complex by facilitating the enzymatic turnover of catalytic subunit RtcB. Acts by promoting the guanylylation of RtcB, a key intermediate step in tRNA ligation. Can also alter the NTP specificity of RtcB such that ATP, dGTP or ITP is used efficiently. | 0.561 |
ACI20058.1 | gyrA | DICTH_1157 | DICTH_1159 | Thiamine transporter. | DNA gyrase, A subunit; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-dependent manner. | 0.561 |