node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ACI18822.1 | ACI19189.1 | DICTH_1221 | DICTH_1225 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Fumarate hydratase, beta subunit; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. | 0.785 |
ACI18822.1 | ACI19748.1 | DICTH_1221 | DICTH_1224 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Conserved hypothetical protein. | 0.787 |
ACI18822.1 | guaA | DICTH_1221 | DICTH_1433 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.414 |
ACI18822.1 | murI | DICTH_1221 | DICTH_1234 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.763 |
ACI18822.1 | rdgB | DICTH_1221 | DICTH_1222 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.812 |
ACI18822.1 | rph | DICTH_1221 | DICTH_1223 | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.894 |
ACI19189.1 | ACI18822.1 | DICTH_1225 | DICTH_1221 | Fumarate hydratase, beta subunit; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | 0.785 |
ACI19189.1 | ACI19748.1 | DICTH_1225 | DICTH_1224 | Fumarate hydratase, beta subunit; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. | Conserved hypothetical protein. | 0.797 |
ACI19189.1 | murI | DICTH_1225 | DICTH_1234 | Fumarate hydratase, beta subunit; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. | Glutamate racemase; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.773 |
ACI19189.1 | rdgB | DICTH_1225 | DICTH_1222 | Fumarate hydratase, beta subunit; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.813 |
ACI19189.1 | rph | DICTH_1225 | DICTH_1223 | Fumarate hydratase, beta subunit; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. | Ribonuclease PH; Phosphorolytic 3'-5' exoribonuclease that plays an important role in tRNA 3'-end maturation. Removes nucleotide residues following the 3'-CCA terminus of tRNAs; can also add nucleotides to the ends of RNA molecules by using nucleoside diphosphates as substrates, but this may not be physiologically important. Probably plays a role in initiation of 16S rRNA degradation (leading to ribosome degradation) during starvation. | 0.797 |
ACI19630.1 | guaA | DICTH_1684 | DICTH_1433 | Nucleotidase; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.931 |
ACI19630.1 | guaB | DICTH_1684 | DICTH_0584 | Nucleotidase; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.925 |
ACI19630.1 | hpt | DICTH_1684 | DICTH_1898 | Nucleotidase; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Hypoxanthine phosphoribosyltransferase; Identified by match to protein family HMM PF00156; match to protein family HMM TIGR01203; Belongs to the purine/pyrimidine phosphoribosyltransferase family. | 0.916 |
ACI19630.1 | rdgB | DICTH_1684 | DICTH_1222 | Nucleotidase; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | Non-canonical purine NTP pyrophosphatase, RdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.902 |
ACI19630.1 | surE | DICTH_1684 | DICTH_0980 | Nucleotidase; Identified by match to protein family HMM PF00149; match to protein family HMM PF02872; Belongs to the 5'-nucleotidase family. | 5'/3'-nucleotidase SurE; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.912 |
ACI19748.1 | ACI18822.1 | DICTH_1224 | DICTH_1221 | Conserved hypothetical protein. | Endoribonuclease L-PSP, putative; Identified by match to protein family HMM PF01042; match to protein family HMM TIGR00004. | 0.787 |
ACI19748.1 | ACI19189.1 | DICTH_1224 | DICTH_1225 | Conserved hypothetical protein. | Fumarate hydratase, beta subunit; Identified by match to protein family HMM PF05683; match to protein family HMM TIGR00723. | 0.797 |
ACI19748.1 | guaA | DICTH_1224 | DICTH_1433 | Conserved hypothetical protein. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.596 |
ACI19748.1 | guaB | DICTH_1224 | DICTH_0584 | Conserved hypothetical protein. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.409 |