STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ACI18672.1Probable methylcobalamin:homocysteine methyltransferase, putative; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family. (325 aa)    
Predicted Functional Partners:
ACI19977.1
5-methyltetrahydropteroyltriglutamate-- homocysteine methyltransferase; Identified by match to protein family HMM PF01717; match to protein family HMM PF08267.
 
  
 
0.981
ahcY
Adenosylhomocysteinase; Identified by match to protein family HMM PF00670; match to protein family HMM PF02826; match to protein family HMM TIGR00936.
  
 
 0.951
ACI18984.1
5-methyltetrahydrofolate-homocysteine methyltransferase; Identified by match to protein family HMM PF02574.
  
 
 0.944
ACI20005.1
S-adenosylmethionine synthetase; Identified by match to protein family HMM PF01941.
  
  
 0.918
metG
methionyl-tRNA synthetase; Is required not only for elongation of protein synthesis but also for the initiation of all mRNA translation through initiator tRNA(fMet) aminoacylation.
    
 0.909
ACI19047.1
Identified by match to protein family HMM PF02310; match to protein family HMM PF02607; match to protein family HMM TIGR02370.
    
  0.901
ACI19022.1
Domain of unknown function, putative; Identified by match to protein family HMM PF01837.
     
  0.900
ACI19480.1
Iron-sulfur cluster-binding protein; Identified by match to protein family HMM PF00037.
     
  0.900
thrB
Homoserine kinase; Catalyzes the ATP-dependent phosphorylation of L-homoserine to L-homoserine phosphate; Belongs to the GHMP kinase family. Homoserine kinase subfamily.
  
 
 0.851
ACI19270.1
Homoserine dehydrogenase; Identified by match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447.
   
 
 0.847
Your Current Organism:
Dictyoglomus thermophilum
NCBI taxonomy Id: 309799
Other names: D. thermophilum H-6-12, Dictyoglomus thermophilum H-6-12
Server load: low (28%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.