STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypAProbable hydrogenase nickel incorporation protein HypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase. (132 aa)    
Predicted Functional Partners:
ACI18581.1
ATPase involved in chromosome partitioning, MinD/MRP superfamily; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
 
 
   0.924
hypF
[NiFe] hydrogenase maturation protein HypF; Identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143.
 
   
 0.764
ACI19952.1
Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF04879.
     
 0.713
ACI18875.1
HoxW protein.
  
  
 0.713
ACI19065.1
NAD-reducing hydrogenase HoxS delta subunit; Identified by match to protein family HMM PF01058.
     
 0.671
ACI19743.1
NAD-reducing hydrogenase HoxS beta subunit; Identified by match to protein family HMM PF00374; Belongs to the [NiFe]/[NiFeSe] hydrogenase large subunit family.
  
  
 0.666
ACI18344.1
MRP/NBP35 family ATP-binding protein; Binds and transfers iron-sulfur (Fe-S) clusters to target apoproteins. Can hydrolyze ATP; Belongs to the Mrp/NBP35 ATP-binding proteins family.
   
   0.596
ACI18984.1
5-methyltetrahydrofolate-homocysteine methyltransferase; Identified by match to protein family HMM PF02574.
       0.519
ACI20052.1
Periplasmic [Fe] hydrogenase 1; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF02256; match to protein family HMM PF02906; match to protein family HMM TIGR02512.
  
 
 0.507
ACI18521.1
Hydrogenase expression/formation protein HypD; Identified by match to protein family HMM PF01924.
 
  
 0.483
Your Current Organism:
Dictyoglomus thermophilum
NCBI taxonomy Id: 309799
Other names: D. thermophilum H-6-12, Dictyoglomus thermophilum H-6-12
Server load: low (24%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.