Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ACI19185.1Pyruvate synthase subunit PorA; Identified by match to protein family HMM PF01855; match to protein family HMM PF02780. (395 aa)    
Predicted Functional Partners:
ACI20007.1
PorB subunit of pyruvate:flavodoxin oxidoreductase; Identified by match to protein family HMM PF02775.
 0.999
ACI18961.1
Pyruvate synthase subunit PorC; Identified by match to protein family HMM PF01558; match to protein family HMM TIGR02175.
 
 0.998
ACI20071.1
Ketoisovalerate oxidoreductase subunit VorD; Identified by match to protein family HMM PF00037; match to protein family HMM TIGR02179.
 
 0.996
ACI19411.1
Pyruvate synthase subunit beta; Identified by match to protein family HMM PF02775; match to protein family HMM TIGR02177.
 
 0.990
ACI18332.1
Oxoglutarate--ferredoxin oxidoreductase, alpha subunit; Identified by match to protein family HMM PF01558; match to protein family HMM PF01855.
 
0.977
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate.
  
 
 0.937
ACI18744.1
Pyruvate dehydrogenase E1 component, beta subunit; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM PF02780.
  
 
 0.934
pyk
Pyruvate kinase; Identified by match to protein family HMM PF00224; match to protein family HMM PF00391; match to protein family HMM PF02887; match to protein family HMM TIGR01064; Belongs to the pyruvate kinase family.
    
 0.931
ilvB
Acetolactate synthase, large subunit, biosynthetic type; Identified by match to protein family HMM PF00205; match to protein family HMM PF02775; match to protein family HMM PF02776; match to protein family HMM TIGR00118.
  
 
 0.914
ppdK
Pyruvate, phosphate dikinase; Identified by match to protein family HMM PF00391; match to protein family HMM PF01326; match to protein family HMM PF02896; match to protein family HMM TIGR01828; Belongs to the PEP-utilizing enzyme family.
    
 0.913
Your Current Organism:
Dictyoglomus thermophilum
NCBI taxonomy Id: 309799
Other names: D. thermophilum H-6-12, Dictyoglomus thermophilum H-6-12
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