STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HVO_0140DUF460 domain protein. (689 aa)    
Predicted Functional Partners:
tfeA
Transcription initiation factor TFE; Transcription factor that plays a role in the activation of archaeal genes transcribed by RNA polymerase. Facilitates transcription initiation by enhancing TATA-box recognition by TATA-box-binding protein (Tbp), and transcription factor B (Tfb) and RNA polymerase recruitment. Not absolutely required for transcription in vitro, but particularly important in cases where Tbp or Tfb function is not optimal. It dynamically alters the nucleic acid-binding properties of RNA polymerases by stabilizing the initiation complex and destabilizing elongation comp [...]
  
     0.667
aglB
Dolichyl-monophosphooligosaccharide-protein glycotransferase AglB; Oligosaccharyl transferase (OST) that catalyzes the initial transfer of a defined glycan (a hexose-linked tetrasaccharide composed of a hexose, 2 hexuronic acids and a methyl ester of hexuronic acid in H.volcanii) from the lipid carrier dolichol-monophosphate to an asparagine residue within an Asn-X-Ser/Thr consensus motif in nascent polypeptide chains, the first step in protein N-glycosylation (Probable). Involved in the assembly of an N-linked pentasaccharide that decorates the S-layer glycoprotein and flagellins (Pr [...]
  
     0.643
cmi2
ArsR family transcription regulator.
  
     0.628
HVO_1577
DUF293 domain protein.
  
     0.623
rpa3
Replication protein A.
  
     0.618
orc9
Orc1-type DNA replication protein; Involved in regulation of DNA replication.
  
     0.597
cdc48d
arNOG05511 family protein (AAA-type ATPase core domain protein); Belongs to the AAA ATPase family.
  
     0.592
rio2
RIO-type serine/threonine protein kinase Rio2.
 
     0.590
HVO_2495
DUF106 family protein.
  
     0.581
scpA
Chromosome segregation and condensation protein ScpA.
  
     0.561
Your Current Organism:
Haloferax volcanii
NCBI taxonomy Id: 309800
Other names: H. volcanii DS2, Haloferax volcanii ATCC 29605, Haloferax volcanii DS2, Haloferax volcanii DSM 3757, Haloferax volcanii str. DS2, Haloferax volcanii strain DS2
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