STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
HVO_2747Putative tRNA-specific adenosine deaminase. (197 aa)    
Predicted Functional Partners:
rpl21e
50S ribosomal protein L21e; Belongs to the eukaryotic ribosomal protein eL21 family.
 
  
 0.909
ths1
Thermosome subunit 1; Molecular chaperone that assists in the folding or refolding of nascent or denatured proteins along with ATP hydrolysis (Probable). ATPase activity is highest in thermosome assemblies containing CCT1:CCT2, followed by assemblies containing CCT1:CCT2:CCT3. Required for thermosome ATPase activity. Not required for growth. Belongs to the TCP-1 chaperonin family.
  
   
 0.781
rpoF
DNA-directed RNA polymerase subunit F.
 
   
 0.766
ksgA
Ribosome biogenesis protein KsgA, 16S rRNA-methylating; Specifically dimethylates two adjacent adenosines in the loop of a conserved hairpin near the 3'-end of 16S rRNA in the 30S particle. May play a critical role in biogenesis of 30S subunits. Belongs to the class I-like SAM-binding methyltransferase superfamily. rRNA adenine N(6)-methyltransferase family. RsmA subfamily.
     
 0.763
tiaS
tRNA(Ile2) 2-agmatinylcytidine synthetase TiaS; ATP-dependent agmatine transferase that catalyzes the formation of 2-agmatinylcytidine (agm2C) at the wobble position (C34) of tRNA(Ile2), converting the codon specificity from AUG to AUA.
  
   
 0.714
tif5A
Translation initiation factor aIF-5A; Functions by promoting the formation of the first peptide bond; Belongs to the eIF-5A family.
 
     0.711
mscS5
Mechanosensitive channel protein MscS.
 
     0.710
prmC
Protein N5-glutamine methyltransferase.
       0.704
HVO_0134
KH domain protein.
 
     0.703
dnaG
DNA primase DnaG; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. Also part of the exosome, which is a complex involved in RNA degradation. Acts as a poly(A)-binding protein that enhances the interaction between heteropolymeric, adenine-rich transcripts and the exosome.
  
     0.698
Your Current Organism:
Haloferax volcanii
NCBI taxonomy Id: 309800
Other names: H. volcanii DS2, Haloferax volcanii ATCC 29605, Haloferax volcanii DS2, Haloferax volcanii DSM 3757, Haloferax volcanii str. DS2, Haloferax volcanii strain DS2
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