STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trd_0171Identified by match to protein family HMM PF00534. (385 aa)    
Predicted Functional Partners:
thiL
Thiamine-monophosphate kinase; Catalyzes the ATP-dependent phosphorylation of thiamine- monophosphate (TMP) to form thiamine-pyrophosphate (TPP), the active form of vitamin B1; Belongs to the thiamine-monophosphate kinase family.
       0.774
trd_0182
Conserved hypothetical protein.
  
   0.609
trd_0179
Identified by match to protein family HMM PF00850.
   
   0.604
trd_0173
glutamyl-tRNA(Gln) amidotransferase subunit A; Identified by match to protein family HMM PF01425; Belongs to the amidase family.
  
    0.603
tsaD
O-sialoglycoprotein endopeptidase; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family.
  
    0.603
trd_0178
Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily.
     
 0.603
trd_0174
Uncharacterized P-loop hydrolase UPF0079; Identified by match to protein family HMM PF02367; match to protein family HMM TIGR00150.
       0.598
trd_0175
Putative glycoprotease family; Identified by match to protein family HMM PF00814.
       0.598
trd_0176
Ribosomal-protein-alanine acetyltransferase; Identified by match to protein family HMM PF00583; match to protein family HMM TIGR01575.
       0.598
trd_0845
Polysaccharide biosynthesis protein; Identified by match to protein family HMM PF01943.
 
  
 0.589
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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