Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
nadBSuccinate dehydrogenase, flavoprotein subunit; Identified by match to protein family HMM PF00890; match to protein family HMM PF01266; match to protein family HMM PF02910; match to protein family HMM PF07992; match to protein family HMM TIGR01812; match to protein family HMM TIGR01816. (576 aa)    
Predicted Functional Partners:
trd_0330
Succinate dehydrogenase iron-sulfur protein; Identified by match to protein family HMM PF00111; match to protein family HMM TIGR00384; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
 0.999
trd_0332
Succinate dehydrogenase, membrane subunit.
 
 0.999
trd_0333
Succinate dehydrogenase, cytochrome subunit; Identified by match to protein family HMM PF01127; match to protein family HMM TIGR02970.
 
 0.999
sucD
succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
 
 0.957
nadC
Nicotinate-nucleotide pyrophosphorylase; Identified by match to protein family HMM PF01729; match to protein family HMM PF02749; match to protein family HMM TIGR00078.
    
 0.915
trd_1469
Aspartate ammonia-lyase; Identified by match to protein family HMM PF00206.
 
  
 0.899
trd_0793
NAD-dependent formate dehydrogenase beta subunit; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF01512.
  
 
 0.885
trd_1303
Aspartate aminotransferase A; Identified by match to protein family HMM PF00155; match to protein family HMM PF00266.
     
 0.812
argH
Argininosuccinate lyase; Identified by match to protein family HMM PF00206; match to protein family HMM TIGR00838.
     
  0.800
nadA
Quinolinate synthetase complex, A subunit; Catalyzes the condensation of iminoaspartate with dihydroxyacetone phosphate to form quinolinate.
   
 0.795
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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