STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trd_0377SUF system FeS assembly protein, NifU family; Identified by match to protein family HMM PF01592; match to protein family HMM TIGR01994. (126 aa)    
Predicted Functional Partners:
iscS
Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily.
 
 0.961
trd_0378
Cysteine desulfurase; Identified by match to protein family HMM PF00266; match to protein family HMM PF01212; match to protein family HMM TIGR01979; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family.
 
 
 0.941
trd_0376
Domain of unknown function domain protein; Identified by match to protein family HMM PF01883.
  
    0.894
trd_0893
DnaJ domain protein; Identified by match to protein family HMM PF00226.
  
 
 0.887
sufD
FeS assembly protein SufD; Identified by match to protein family HMM PF01458; match to protein family HMM TIGR01981.
  
  
 0.874
sufC
FeS assembly ATPase SufC; Identified by match to protein family HMM PF00005; match to protein family HMM TIGR01978.
  
  
 0.844
sufB
FeS assembly protein SufB; Identified by match to protein family HMM PF01458; match to protein family HMM TIGR01980.
  
  
 0.808
trd_0717
Probable cysteine desulfurase; Identified by match to protein family HMM PF00266.
 
 
 0.803
trd_1567
Cysteine desulfurase/cysteine sulfinate desulfinase; Identified by match to protein family HMM PF00155; match to protein family HMM PF00266; match to protein family HMM PF01041; match to protein family HMM PF01053; match to protein family HMM PF01212.
 
 
 0.801
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.795
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.