| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| aceF | sucD | trd_1735 | trd_1803 | Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.900 |
| aceF | trd_0804 | trd_1735 | trd_0804 | Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640. | 0.802 |
| aceF | trd_1560 | trd_1735 | trd_1560 | Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | Methylmalonyl Coenzyme A mutase; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641. | 0.803 |
| mdh | sucD | trd_0921 | trd_1803 | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.564 |
| mdh | trd_0804 | trd_0921 | trd_0804 | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640. | 0.825 |
| mdh | trd_1560 | trd_0921 | trd_1560 | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | Methylmalonyl Coenzyme A mutase; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641. | 0.825 |
| pth | trd_0803 | trd_0807 | trd_0803 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | ArgK protein; Identified by match to protein family HMM PF03308. | 0.575 |
| pth | trd_0804 | trd_0807 | trd_0804 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640. | 0.575 |
| pth | trd_0805 | trd_0807 | trd_0805 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Putative ATP:corrinoid adenosyltransferase BtuR/CobO/CobP. | 0.605 |
| pth | trd_0806 | trd_0807 | trd_0806 | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | Hypothetical protein; Identified by glimmer; putative. | 0.648 |
| sucB | sucD | trd_0561 | trd_1803 | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 0.954 |
| sucB | trd_0804 | trd_0561 | trd_0804 | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640. | 0.802 |
| sucB | trd_1560 | trd_0561 | trd_1560 | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Methylmalonyl Coenzyme A mutase; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641. | 0.803 |
| sucD | aceF | trd_1803 | trd_1735 | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817. | 0.900 |
| sucD | mdh | trd_1803 | trd_0921 | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family. | 0.564 |
| sucD | sucB | trd_1803 | trd_0561 | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | 2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.954 |
| sucD | trd_0804 | trd_1803 | trd_0804 | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640. | 0.909 |
| sucD | trd_1560 | trd_1803 | trd_1560 | succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit. | Methylmalonyl Coenzyme A mutase; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641. | 0.909 |
| trd_0803 | pth | trd_0803 | trd_0807 | ArgK protein; Identified by match to protein family HMM PF03308. | peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family. | 0.575 |
| trd_0803 | trd_0804 | trd_0803 | trd_0804 | ArgK protein; Identified by match to protein family HMM PF03308. | Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640. | 0.997 |