trd_0804 protein (Thermomicrobium roseum) - STRING interaction network

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Score

trd_0804

Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640. (136 aa)

Predicted Functional Partners:

trd_0803

0.999

trd_1560

0.999

trd_1923

0.976

sucD

0.906

mdh

0.823

trd_0805

0.808

sucB

0.803

aceF

0.803

trd_0806

0.682

pth

0.575

Your Current Organism:

Thermomicrobium roseum

NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
aceF	sucB	trd_1735	trd_0561	Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.456
aceF	sucD	trd_1735	trd_1803	Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.888
aceF	trd_0804	trd_1735	trd_0804	Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640.	0.803
aceF	trd_1560	trd_1735	trd_1560	Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	Methylmalonyl Coenzyme A mutase; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641.	0.803
mdh	sucD	trd_0921	trd_1803	Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.	succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.517
mdh	trd_0804	trd_0921	trd_0804	Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.	Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640.	0.823
mdh	trd_1560	trd_0921	trd_1560	Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.	Methylmalonyl Coenzyme A mutase; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641.	0.822
pth	trd_0803	trd_0807	trd_0803	peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.	ArgK protein; Identified by match to protein family HMM PF03308.	0.575
pth	trd_0804	trd_0807	trd_0804	peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.	Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640.	0.575
pth	trd_0805	trd_0807	trd_0805	peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.	Putative ATP:corrinoid adenosyltransferase BtuR/CobO/CobP.	0.605
pth	trd_0806	trd_0807	trd_0806	peptidyl-tRNA hydrolase; The natural substrate for this enzyme may be peptidyl-tRNAs which drop off the ribosome during protein synthesis. Belongs to the PTH family.	Hypothetical protein; Identified by glimmer; putative.	0.648
sucB	aceF	trd_0561	trd_1735	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	0.456
sucB	sucD	trd_0561	trd_1803	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	0.949
sucB	trd_0804	trd_0561	trd_0804	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640.	0.803
sucB	trd_1560	trd_0561	trd_1560	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	Methylmalonyl Coenzyme A mutase; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641.	0.803
sucD	aceF	trd_1803	trd_1735	succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Pyruvate dehydrogenase complex, E2 component, dihydrolipoamide acetyltransferase; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.	0.888
sucD	mdh	trd_1803	trd_0921	succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.	0.517
sucD	sucB	trd_1803	trd_0561	succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	2-oxoglutarate dehydrogenase, E2 component, dihydrolipoamide succinyltransferase; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).	0.949
sucD	trd_0804	trd_1803	trd_0804	succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Sbm protein; Identified by match to protein family HMM PF02310; match to protein family HMM TIGR00640.	0.906
sucD	trd_1560	trd_1803	trd_1560	succinyl-CoA synthetase alpha chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.	Methylmalonyl Coenzyme A mutase; Identified by match to protein family HMM PF01642; match to protein family HMM TIGR00641.	0.906