STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trd_1114DNA polymerase III epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM TIGR00573. (228 aa)    
Predicted Functional Partners:
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
 0.970
trd_0738
DNA polymerase III alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.
   
 0.968
trd_0002
DNA polymerase III tau and gamma subunits; Identified by match to protein family HMM TIGR00678.
  
 0.961
trd_1116
CBS domain protein; Identified by match to protein family HMM PF00027; match to protein family HMM PF00571; match to protein family HMM PF03445.
    0.961
dnaX
DNA polymerase III subunit gamma/tau; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
   
 0.953
trd_0385
Putative DNA polymerase III, epsilon chain (EC); Identified by match to protein family HMM PF00929.
  
  
  0.938
trd_0207
DNA polymerase III, epsilon subunit; Identified by match to protein family HMM PF00929; match to protein family HMM PF01541; match to protein family HMM PF02151; match to protein family HMM TIGR00573.
     
0.905
trd_1113
Putative sodium/solute symporter; Identified by match to protein family HMM PF00474; match to protein family HMM TIGR00813; Belongs to the sodium:solute symporter (SSF) (TC 2.A.21) family.
 
    0.614
trd_1117
Acetyl-coenzyme A synthetase; Identified by match to protein family HMM PF00501.
  
    0.561
trd_1112
Conserved hypothetical protein.
 
     0.550
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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