STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trd_13872-oxo-hepta-3-ene-1,7-dioic acid hydratase; Identified by match to protein family HMM PF01689. (266 aa)    
Predicted Functional Partners:
trd_1392
4-hydroxy-2-oxovalerate aldolase; Catalyzes the retro-aldol cleavage of 4-hydroxy-2- oxopentanoate to pyruvate and acetaldehyde. Is involved in the meta- cleavage pathway for the degradation of aromatic compounds. Belongs to the 4-hydroxy-2-oxovalerate aldolase family.
 
 
 0.992
trd_1390
Putative hydrolase, alpha/beta fold family; Identified by match to protein family HMM PF00561.
 
 
 0.988
trd_1393
Acetaldehyde dehydrogenase; Catalyzes the conversion of acetaldehyde to acetyl-CoA, using NAD(+) and coenzyme A. Is the final enzyme in the meta-cleavage pathway for the degradation of aromatic compounds.
  
 0.974
trd_1388
4-oxalocrotonate decarboxylase; Identified by match to protein family HMM PF01689.
 
    
0.866
trd_1389
Putative tautomerase; Identified by match to protein family HMM PF01361; Belongs to the 4-oxalocrotonate tautomerase family.
     
 0.797
trd_1626
2-dehydro-3-deoxyglucarate aldolase; Identified by match to protein family HMM PF03328; Belongs to the HpcH/HpaI aldolase family.
  
 0.741
trd_1396
Catechol 2,3-dioxygenase; Identified by match to protein family HMM PF00903.
  
 0.703
trd_1129
2,4-dihydroxyhept-2-ene-1,7-dioic acid aldolase; Identified by match to protein family HMM PF03328; Belongs to the HpcH/HpaI aldolase family.
  
 0.701
trd_0322
Catechol 2,3-dioxygenase; Identified by match to protein family HMM PF00903; match to protein family HMM TIGR03211.
  
 0.682
trd_1391
StyB protein; Identified by match to protein family HMM PF01613.
     
 0.680
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.