STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trd_1468Aldehyde dehydrogenase (nadp) family protein; Identified by match to protein family HMM PF00171; match to protein family HMM PF05893. (478 aa)    
Predicted Functional Partners:
fmt
methionyl-tRNA formyltransferase; Attaches a formyl group to the free amino group of methionyl- tRNA(fMet). The formyl group appears to play a dual role in the initiator identity of N-formylmethionyl-tRNA by promoting its recognition by IF2 and preventing the misappropriation of this tRNA by the elongation apparatus; Belongs to the Fmt family.
 
    
 0.841
tal
Transaldolase and glucose-6-phosphate isomerase bifunctional protein; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway; Belongs to the GPI family.
  
 
 0.658
trd_1685
Putative phenylacetate-CoA ligase.
  
 
 0.658
nuoI
Nadh-quinone oxidoreductase chain i; NDH-1 shuttles electrons from NADH, via FMN and iron-sulfur (Fe-S) centers, to quinones in the respiratory chain. The immediate electron acceptor for the enzyme in this species is believed to be ubiquinone. Couples the redox reaction to proton translocation (for every two electrons transferred, four hydrogen ions are translocated across the cytoplasmic membrane), and thus conserves the redox energy in a proton gradient.
 
  
 0.541
trd_1469
Aspartate ammonia-lyase; Identified by match to protein family HMM PF00206.
  
  
 0.535
trd_1492
Dihydrolipoamide S-acetyltransferase; Identified by match to protein family HMM PF00364; match to protein family HMM PF00561; match to protein family HMM PF02129; match to protein family HMM PF02817.
  
 
 0.521
trd_1471
Formate dehydrogenase, alpha subunit homolog; Identified by match to protein family HMM PF00037; match to protein family HMM PF00111; match to protein family HMM PF00384; match to protein family HMM PF04879.
     
 0.498
trd_1105
Glutamate synthase [nadph] large chain precursor; Identified by match to protein family HMM PF00310; match to protein family HMM PF01493; match to protein family HMM PF01645; match to protein family HMM PF04898.
  
  
 0.494
trd_0194
1,3-propanediol dehydrogenase; Identified by match to protein family HMM PF00465.
 
 
 0.491
trd_0005
Tetratricopeptide repeat family; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00515; match to protein family HMM PF07719; match to protein family HMM PF07721.
   
 0.486
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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