STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
lysXLysine biosynthesis enzyme LysX; Identified by match to protein family HMM PF01071; match to protein family HMM PF02222; match to protein family HMM PF02655; match to protein family HMM PF08443; match to protein family HMM TIGR00768; match to protein family HMM TIGR02144; Belongs to the RimK family. (294 aa)    
Predicted Functional Partners:
argB
Acetylglutamate kinase; Catalyzes the phosphorylation of LysW-gamma-alpha- aminoadipate; Belongs to the acetylglutamate kinase family. LysZ subfamily.
 
  
 0.990
lysW
Lysine biosynthesis protein LysW; Identified by match to protein family HMM TIGR01206.
 
   
 0.955
lysK
N-acetyl-ornithine/N-acetyl-lysine deacetylase subfamily; Catalyzes the release of L-lysine from [LysW]-gamma-L-lysine.
 
  
 0.943
trd_0027
Aminotransferase, class I and II; Identified by match to protein family HMM PF00155.
     
  0.900
trd_1792
Identified by match to protein family HMM PF00155.
     
  0.900
argC
N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of [LysW]- aminoadipate 6-phosphate to yield [LysW]-aminoadipate 6-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 1 subfamily. LysY sub-subfamily.
 
  
 0.893
trd_1521
Putative lysine biosynthesis enzyme LysX; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF08443.
 
    
0.835
lysJ
Acetylornithine aminotransferase; Catalyzes the transfer of the amino group of L-glutamate to [LysW]-aminoadipate 6-semialdehyde, generating [LysW]-gamma-L-lysine. Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. LysJ subfamily.
     
 0.692
trd_1517
Conserved hypothetical protein; Identified by match to protein family HMM PF08241; match to protein family HMM PF08242.
       0.660
trd_1514
Hypothetical protein; Identified by glimmer; putative.
       0.642
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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