STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypF[NiFe] hydrogenase maturation protein HypF; Identified by match to protein family HMM PF00708; match to protein family HMM PF01300; match to protein family HMM PF07503; match to protein family HMM TIGR00143. (758 aa)    
Predicted Functional Partners:
hypE
Hydrogenase expression/formation protein HypE; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769; match to protein family HMM TIGR02124.
 
 
 0.986
hypD
Hydrogenase expression/formation protein HypD; Identified by match to protein family HMM PF01924; match to protein family HMM TIGR00075.
 
  
 0.964
hypC
Hydrogenase assembly chaperone HypC/HupF; Identified by match to protein family HMM PF01455; match to protein family HMM TIGR00074.
 
 
 0.952
hypB
Hydrogenase accessory protein HypB; Identified by match to protein family HMM PF02492; match to protein family HMM TIGR00073.
 
   
 0.941
trd_0606
Hydrogenase expression/formation; Identified by match to protein family HMM PF00586; match to protein family HMM PF02769.
 
 
 0.922
hypA
Probable hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.913
trd_1865
Phosphoheptose isomerase.
     
 0.810
trd_0023
Hydrogenase expression/formation protein HypE; Identified by match to protein family HMM PF02769.
 
 
 0.807
trd_1868
Hydrogenase maturation factor.
  
 
 0.786
trd_1864
Glutaredoxin 3; Identified by match to protein family HMM PF00462.
       0.773
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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