Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-expression
Experiments
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[Homology]
Score
trd_1963ComE operon protein 3; Identified by match to protein family HMM PF00753. (293 aa)    
Predicted Functional Partners:
trd_0672
ComE-like competence protein; Identified by match to protein family HMM PF03772; match to protein family HMM TIGR00360.
   
 0.925
pgsA
CDP-diacylglycerol--glycerol-3-phosphate 3 -phosphatidyltransferase (pgsA); Identified by match to protein family HMM PF01066; Belongs to the CDP-alcohol phosphatidyltransferase class-I family.
       0.782
trd_1961
Putative peptidase; Identified by match to protein family HMM PF01476.
       0.773
trd_1962
Hypothetical protein; Identified by glimmer; putative.
       0.773
trd_1965
Glycosyl transferase; Identified by match to protein family HMM PF00534.
       0.773
glyA
Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
      0.767
trd_1966
Hypothetical protein; Identified by glimmer; putative.
       0.565
trd_0671
Competence protein ComEA helix-hairpin-helix repeat region; An automated process has identified a potential problem with this gene model; the current end5 and/or the end3 may need to extended or the current gene model may need to be merged with a neighboring gene model; the current gene model (or a revised gene model) may contain a frame shift; identified by match to protein family HMM PF00633; match to protein family HMM TIGR00426.
 
  
 0.489
trd_1703
Serine proteinase; Identified by match to protein family HMM PF00082; match to protein family HMM PF05922; Belongs to the peptidase S8 family.
 
     0.435
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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