Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
trd_1968Putative penicillin-binding protein 1A; Identified by match to protein family HMM PF00905; match to protein family HMM PF00912. (842 aa)    
Predicted Functional Partners:
trd_0058
Identified by match to protein family HMM PF00905; match to protein family HMM PF03717.
 
 
 
 0.909
trd_1927
Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM TIGR03423.
 
 
 
 0.886
trd_1373
Penicillin-binding protein 2; Identified by match to protein family HMM PF00905; match to protein family HMM PF03717; match to protein family HMM PF05223; match to protein family HMM TIGR03423.
 
 
 
 0.867
trd_0835
PbpA; Identified by match to protein family HMM PF00905.
 
 
 
 0.846
ftsW
Cell division protein FtsW; Identified by match to protein family HMM PF01098; match to protein family HMM TIGR02614; Belongs to the SEDS family.
  
 
 
 0.696
dnaN
DNA polymerase III, beta subunit; Confers DNA tethering and processivity to DNA polymerases and other proteins. Acts as a clamp, forming a ring around DNA (a reaction catalyzed by the clamp-loading complex) which diffuses in an ATP- independent manner freely and bidirectionally along dsDNA. Initially characterized for its ability to contact the catalytic subunit of DNA polymerase III (Pol III), a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria; Pol III exhibits 3'-5' exonuclease proofreading activity. The beta chain is required for initiation of [...]
  
  
 0.693
trd_1435
Rod shape-determining protein RodA; Identified by match to protein family HMM PF01098; Belongs to the SEDS family.
  
 
 
 0.693
trd_1939
Lipoprotein precursor; Identified by match to protein family HMM PF01476; match to protein family HMM PF01551.
  
   
 0.690
recG
ATP-dependent DNA helicase RecG; Critical role in recombination and DNA repair. Helps process Holliday junction intermediates to mature products by catalyzing branch migration. Has a DNA unwinding activity characteristic of a DNA helicase with a 3'- to 5'- polarity. Unwinds branched duplex DNA (Y- DNA); Belongs to the helicase family. RecG subfamily.
 
   
 0.683
trd_0002
DNA polymerase III tau and gamma subunits; Identified by match to protein family HMM TIGR00678.
 
  
 0.672
Your Current Organism:
Thermomicrobium roseum
NCBI taxonomy Id: 309801
Other names: T. roseum DSM 5159, Thermomicrobium roseum DSM 5159
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