STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
CTN_0202Putative diguanylate cyclase. (209 aa)    
Predicted Functional Partners:
pdxT
Glutamine amidotransferase subunit pdxT; Catalyzes the hydrolysis of glutamine to glutamate and ammonia as part of the biosynthesis of pyridoxal 5'-phosphate. The resulting ammonia molecule is channeled to the active site of PdxS.
       0.811
pdxS
Pyridoxal biosynthesis lyase pdxS; Catalyzes the formation of pyridoxal 5'-phosphate from ribose 5-phosphate (RBP), glyceraldehyde 3-phosphate (G3P) and ammonia. The ammonia is provided by the PdxT subunit. Can also use ribulose 5- phosphate and dihydroxyacetone phosphate as substrates, resulting from enzyme-catalyzed isomerization of RBP and G3P, respectively. Belongs to the PdxS/SNZ family.
       0.811
CTN_0198
Pyrazinamidase/nicotinamidase-related protein.
       0.773
CTN_0199
Nicotinic acid phosphoribosyltransferase-like protein; Belongs to the NAPRTase family.
       0.773
CTN_0203
Integral membrane protein-like protein.
       0.773
CTN_0204
Uncharacterized protein.
       0.773
CTN_0205
Response regulator.
       0.773
CTN_0206
Regulatory protein.
       0.773
CTN_0207
Hypothetical Protein.
       0.773
CTN_0208
Putative uncharacterized protein.
       0.598
Your Current Organism:
Thermotoga neapolitana
NCBI taxonomy Id: 309803
Other names: T. neapolitana DSM 4359, Thermotoga neapolitana ATCC 49049, Thermotoga neapolitana DSM 4359, Thermotoga neapolitana JCM 10099, Thermotoga neapolitana NS-E
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