STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
folBDihydroneopterin aldolase; Catalyzes the conversion of 7,8-dihydroneopterin to 6- hydroxymethyl-7,8-dihydropterin. (142 aa)    
Predicted Functional Partners:
folK
2-amino-4-hydroxy-6- hydroxymethyldihydropteridine pyrophosphokinase; Identified by match to protein family HMM PF01288; match to protein family HMM TIGR01498.
 
 
 0.994
folP
Dihydropteroate synthase; Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
 
 
 0.993
SRU_0238
Alkaline phosphatase family protein, putative; Identified by match to protein family HMM PF00245; Belongs to the alkaline phosphatase family.
     
  0.900
SRU_2450
Alkaline phosphatase, putative; Identified by match to protein family HMM PF00245; match to protein family HMM TIGR01409; Belongs to the alkaline phosphatase family.
     
  0.900
folE
GTP cyclohydrolase I; Identified by match to protein family HMM PF01227; match to protein family HMM TIGR00063.
 
  
 0.899
SRU_0760
Carbohydrate kinase, PfkB family; Identified by match to protein family HMM PF00294.
       0.592
SRU_1685
Chorismate binding enzyme; Identified by match to protein family HMM PF00425; match to protein family HMM TIGR00553.
  
  
 0.529
SRU_2420
Dihydrofolate synthetase; Identified by match to protein family HMM PF02875; match to protein family HMM TIGR01499; Belongs to the folylpolyglutamate synthase family.
  
  
 0.508
ribD
Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family.
  
  
 0.498
rdgB
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.487
Your Current Organism:
Salinibacter ruber
NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855
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