STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
thiGThiazole biosynthesis protein ThiG; Catalyzes the rearrangement of 1-deoxy-D-xylulose 5-phosphate (DXP) to produce the thiazole phosphate moiety of thiamine. Sulfur is provided by the thiocarboxylate moiety of the carrier protein ThiS. In vitro, sulfur can be provided by H(2)S. (273 aa)    
Predicted Functional Partners:
thiO
Glycine oxidase ThiO; Identified by match to protein family HMM PF01266; match to protein family HMM TIGR02352.
 
 0.999
thiS
Thiamine biosynthesis protein ThiS; Identified by match to protein family HMM PF02597; match to protein family HMM TIGR01683.
  
 
 0.996
SRU_2042
MoeZ/MoeB domain family; Identified by match to protein family HMM PF00581; match to protein family HMM PF00899; match to protein family HMM PF05237.
  
 0.988
thiE
Thiamine-phosphate pyrophosphorylase; Condenses 4-methyl-5-(beta-hydroxyethyl)thiazole monophosphate (THZ-P) and 2-methyl-4-amino-5-hydroxymethyl pyrimidine pyrophosphate (HMP-PP) to form thiamine monophosphate (TMP). Belongs to the thiamine-phosphate synthase family.
  
 0.925
SRU_1236
Thiamine-phosphate pyrophosphorylase; Identified by match to protein family HMM PF02581.
 
  
 0.898
thiD
Phosphomethylpyrimidine kinase; Identified by match to protein family HMM TIGR00097.
  
  
 0.809
SRU_2041
ThiS family, putative; Identified by match to protein family HMM PF02597.
   
 
 0.795
SRU_1511
Hypothetical protein; Identified by Glimmer2; putative.
  
  
 0.727
SRU_0332
TENA/THI-4 family; Catalyzes an amino-pyrimidine hydrolysis reaction at the C5' of the pyrimidine moiety of thiamine compounds, a reaction that is part of a thiamine salvage pathway; Belongs to the TenA family.
  
  
 0.687
SRU_1232
Glycine oxidase, putative; Identified by match to protein family HMM PF01266.
  
  
 0.650
Your Current Organism:
Salinibacter ruber
NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855
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