node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
SRU_1251 | proB | SRU_1251 | SRU_1252 | ABC-type multidrug transport system, ATPase component; Identified by match to protein family HMM PF00005. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.572 |
SRU_2217 | ThrA | SRU_2217 | SRU_0691 | Aminotransferase, class III superfamily; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | 0.470 |
SRU_2217 | proA | SRU_2217 | SRU_1253 | Aminotransferase, class III superfamily; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.466 |
SRU_2217 | proB | SRU_2217 | SRU_1252 | Aminotransferase, class III superfamily; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.489 |
SRU_2217 | proC | SRU_2217 | SRU_1560 | Aminotransferase, class III superfamily; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.517 |
SRU_2217 | serC | SRU_2217 | SRU_2207 | Aminotransferase, class III superfamily; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.427 |
ThrA | SRU_2217 | SRU_0691 | SRU_2217 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | Aminotransferase, class III superfamily; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.470 |
ThrA | proA | SRU_0691 | SRU_1253 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 0.526 |
ThrA | proB | SRU_0691 | SRU_1252 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.532 |
ThrA | proC | SRU_0691 | SRU_1560 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.552 |
ThrA | ribBA | SRU_0691 | SRU_0012 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.488 |
ThrA | serC | SRU_0691 | SRU_2207 | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.630 |
glyS | proB | SRU_2334 | SRU_1252 | glycyl-tRNA synthetase; Catalyzes the attachment of glycine to tRNA(Gly). Belongs to the class-II aminoacyl-tRNA synthetase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.543 |
proA | SRU_2217 | SRU_1253 | SRU_2217 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Aminotransferase, class III superfamily; Identified by match to protein family HMM PF00202; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.466 |
proA | ThrA | SRU_1253 | SRU_0691 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Bifunctional aspartokinase/homoserine dehydrogenase I; Identified by match to protein family HMM PF00696; match to protein family HMM PF00742; match to protein family HMM PF01842; match to protein family HMM PF03447; match to protein family HMM TIGR00657. | 0.526 |
proA | proB | SRU_1253 | SRU_1252 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Glutamate 5-kinase; Catalyzes the transfer of a phosphate group to glutamate to form L-glutamate 5-phosphate. | 0.999 |
proA | proC | SRU_1253 | SRU_1560 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Pyrroline-5-carboxylate reductase; Catalyzes the reduction of 1-pyrroline-5-carboxylate (PCA) to L-proline. | 0.746 |
proA | pruA | SRU_1253 | SRU_1517 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 1-pyrroline-5-carboxylate dehydrogenase; Identified by match to protein family HMM PF00171; match to protein family HMM TIGR01236. | 0.906 |
proA | ribBA | SRU_1253 | SRU_0012 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase/GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.486 |
proA | serC | SRU_1253 | SRU_2207 | Gamma-glutamyl phosphate reductase; Catalyzes the NADPH-dependent reduction of L-glutamate 5- phosphate into L-glutamate 5-semialdehyde and phosphate. The product spontaneously undergoes cyclization to form 1-pyrroline-5-carboxylate. Belongs to the gamma-glutamyl phosphate reductase family. | Phosphoserine aminotransferase; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.443 |