STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadKATP-NAD kinase, putative; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP. (263 aa)    
Predicted Functional Partners:
nadD
Nicotinate (nicotinamide) nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
 
 
 0.954
nadE
NAD(+) synthase (glutamine-hydrolysing); Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
 
  
 0.952
cobB
Transcriptional regulator, Sir2 family; Identified by match to protein family HMM PF02146; Belongs to the sirtuin family. Class III subfamily.
  
 
 0.918
SRU_2205
Conserved hypothetical protein.
     
 0.914
SRU_2206
Alanine dehydrogenase/PNT, N-terminal domain family; Identified by match to protein family HMM PF01262; match to protein family HMM PF05222.
     
 0.914
SRU_2204
NAD(P) transhydrogenase beta subunit superfamily; The transhydrogenation between NADH and NADP is coupled to respiration and ATP hydrolysis and functions as a proton pump across the membrane; Belongs to the PNT beta subunit family.
     
 0.907
fumC
Fumarate hydratase class II; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
 
     0.611
SRU_0531
Inositol-1-monophosphatase; Identified by match to protein family HMM PF00459; Belongs to the inositol monophosphatase superfamily.
 
    0.592
SRU_0697
GAF domain protein; Identified by match to protein family HMM PF01590.
 
 
    0.545
recN
DNA repair protein RecN; May be involved in recombinational repair of damaged DNA.
 
  
 0.541
Your Current Organism:
Salinibacter ruber
NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855
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