STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRU_1791Methylmalonyl-CoA mutase superfamily; Identified by match to protein family HMM PF01642. (648 aa)    
Predicted Functional Partners:
SRU_1689
methylmalonyll-CoA mutase; Identified by match to protein family HMM PF01642; match to protein family HMM PF03308.
 
 
0.999
mutA
methylmalonyl-CoA mutase, beta subunit; Identified by match to protein family HMM PF01642; match to protein family HMM PF02310; match to protein family HMM TIGR00640; match to protein family HMM TIGR00641.
 
0.999
SRU_1793
LAO/AO transport system ATPase; Identified by match to protein family HMM PF03308; match to protein family HMM TIGR00750.
  
 0.980
sucD
succinyl-CoA synthetase, alpha subunit; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and nucleotide specificity is provided by the beta subunit.
    
 0.944
sucC
succinyl-CoA synthetase beta chain; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit.
  
 
 0.930
pycA
Pyruvate carboxylase; Identified by match to protein family HMM PF00364.
  
 
 0.886
SRU_0423
Pyruvate synthase; Identified by match to protein family HMM PF01558; match to protein family HMM PF01855.
    
 0.879
SRU_0424
2-oxoacid:ferredoxin oxidoreductase, beta subunit; Identified by match to protein family HMM PF02775.
    
 0.867
citA
Citrate synthase; Identified by match to protein family HMM PF00285; match to protein family HMM TIGR01800; Belongs to the citrate synthase family.
    
 0.867
mdh
Malate dehydrogenase, NAD-dependent; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 3 family.
    
 0.862
Your Current Organism:
Salinibacter ruber
NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.