STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRU_1806Probable ATP-dependent DNA helicase; Identified by match to protein family HMM PF00580; Belongs to the helicase family. UvrD subfamily. (1114 aa)    
Predicted Functional Partners:
SRU_1807
Hypothetical protein; Identified by Glimmer2; putative.
 
 
 0.997
SRU_0919
Putative deoxyribonuclease.
  
 
 0.859
SRU_0718
Probable ATP-dependent DNA helicase; Identified by match to protein family HMM PF00580.
 
  
 0.643
dnaE
DNA polymerase III, alpha subunit; Identified by match to protein family HMM PF01336; match to protein family HMM PF02811; match to protein family HMM PF07733; match to protein family HMM TIGR00594.
 
  
 0.559
recA
recA protein; Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage; Belongs to the RecA family.
  
 
 0.530
ligA
DNA ligase, NAD-dependent; DNA ligase that catalyzes the formation of phosphodiester linkages between 5'-phosphoryl and 3'-hydroxyl groups in double- stranded DNA using NAD as a coenzyme and as the energy source for the reaction. It is essential for DNA replication and repair of damaged DNA.
  
 
 0.503
SRU_1808
Protein parB; Identified by match to protein family HMM PF00565.
       0.495
polA
DNA polymerase I; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family.
     
 0.480
SRU_2289
Putative helicase; Identified by match to protein family HMM PF00271; match to protein family HMM PF01844; match to protein family HMM PF04851.
     
 0.461
SRU_0607
Putative mannose-1-phosphate guanyltransferase; Identified by match to protein family HMM PF00483; match to protein family HMM PF00571.
 
    0.444
Your Current Organism:
Salinibacter ruber
NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.