STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRU_1938Phosphoesterase, putative subfamily; Identified by match to protein family HMM PF00149; match to protein family HMM TIGR00040. (174 aa)    
Predicted Functional Partners:
rdgB
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
  
  
 0.819
SRU_2404
Conserved hypothetical protein; Identified by match to protein family HMM PF00023.
    
 
 0.759
SRU_0029
Conserved hypothetical protein; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits.
  
     0.564
SRU_1327
Conserved hypothetical protein.
  
     0.535
SRU_1937
Metallo-beta-lactamase superfamily, putative; Identified by match to protein family HMM PF00753; Belongs to the UPF0173 family.
       0.501
SRU_2436
tRNA nucleotidyltransferase/poly(A) polymerase family protein; Identified by match to protein family HMM PF01743; match to protein family HMM PF01966; match to protein family HMM TIGR00277; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family.
 
 
 0.440
SRU_2005
Putative esterase superfamily; Identified by match to protein family HMM PF00756.
  
  
 0.432
Your Current Organism:
Salinibacter ruber
NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.