STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
SRU_1970Pyruvate dehydrogenase E1 component, beta subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (327 aa)    
Predicted Functional Partners:
SRU_1969
Dihydrolipoyllysine-residue acetyltransferase component of pyruvatedehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
pdhA
Pyruvate dehydrogenase E1 component, alpha subunit; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.999
sucA
2-oxoglutarate dehydrogenase, E1 component; Identified by match to protein family HMM PF00198; match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM TIGR00239.
  
 0.990
lpdA
Dihydrolipoamide dehydrogenase; Identified by match to protein family HMM PF00070; match to protein family HMM PF02852; match to protein family HMM PF07992; match to protein family HMM TIGR01350.
 0.990
SRU_0811
2-oxo acid dehydrogenases acyltransferase (catalytic domain) protein; Identified by match to protein family HMM PF00198; match to protein family HMM PF00364; match to protein family HMM PF02817.
 0.971
SRU_0423
Pyruvate synthase; Identified by match to protein family HMM PF01558; match to protein family HMM PF01855.
   
 
 0.934
pycA
Pyruvate carboxylase; Identified by match to protein family HMM PF00364.
  
 0.930
SRU_1786
NAD-dependent malic enzyme; Identified by match to protein family HMM PF00390; match to protein family HMM PF01842; match to protein family HMM PF03949.
  
 
 0.920
ldh
L-lactate dehydrogenase; Catalyzes the conversion of lactate to pyruvate. Belongs to the LDH/MDH superfamily. LDH family.
   
 0.918
SRU_1966
Pyruvate dehydrogenase beta subunit; Identified by match to protein family HMM PF00676; match to protein family HMM PF02779; match to protein family HMM PF02780.
 
0.918
Your Current Organism:
Salinibacter ruber
NCBI taxonomy Id: 309807
Other names: S. ruber DSM 13855, Salinibacter ruber DSM 13855, Salinibacter ruber str. DSM 13855, Salinibacter ruber strain DSM 13855
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.