Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101068527Toll-like receptor 18. (871 aa)    
Predicted Functional Partners:
myd88
Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.
   
0.983
tirap
Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.
   
 0.956
LOC101078355
Toll interacting protein.
    
 0.937
RAC1
Uncharacterized protein.
   
 0.923
LOC101067160
Rac family small GTPase 1b.
   
 0.923
tlr1
Toll-like receptor 1.
     
0.914
tlr2
Toll-like receptor 2.
     
0.911
lrr1
Zgc:77287.
    
 0.558
tlr5
TIR domain-containing protein; Belongs to the Toll-like receptor family.
   
 
0.549
il10
Interleukin 10.
   
 
 0.519
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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