Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
LOC101067334Protein disulfide-isomerase. (496 aa)    
Predicted Functional Partners:
LOC101074526
Calreticulin.
   
 0.974
calr
Calreticulin.
   
 0.973
hspa5
Heat shock protein 5; Belongs to the heat shock protein 70 family.
   
 0.945
pdia3
Protein disulfide-isomerase.
  
  
 
0.902
hsp90b1
Heat shock protein 90, beta (grp94), member 1.
   
 0.855
tapbp
TAP binding protein (tapasin), tandem duplicate 2.
    
 0.854
ero1b
Endoplasmic reticulum oxidoreductase beta.
   
 0.790
ero1a
Endoplasmic reticulum oxidoreductase alpha.
   
 0.790
LOC101070859
Calnexin.
   
 0.777
LOC101069714
Uncharacterized protein.
   
 0.774
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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