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STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
casc3Casc3 exon junction complex subunit. (740 aa)    
Predicted Functional Partners:
rbm8a
RNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs.
   
 0.996
eif4a3
Eukaryotic translation initiation factor 4A3; Belongs to the DEAD box helicase family.
    
 0.971
LOC101074452
Mago homolog, exon junction complex subunit.
    
 0.966
LOC101077614
TPR_REGION domain-containing protein.
    
  0.921
LOC101064659
Uncharacterized protein.
    
 0.868
UPF1
Putative regulator of nonsense transcripts 1; RNA-dependent helicase and ATPase required for nonsense- mediated decay (NMD) of mRNAs containing premature stop codons. Is recruited to mRNAs upon translation termination and undergoes a cycle of phosphorylation and dephosphorylation; its phosphorylation appears to be a key step in NMD. The formation of an rent1-rent2-rent3 surveillance complex is believed to activate NMD (By similarity).
    
 0.868
upf3b
UPF3B regulator of nonsense mediated mRNA decay.
    
 0.855
UPF2
UPF2 regulator of nonsense mediated mRNA decay.
    
 0.843
upf3a
UPF3A regulator of nonsense mediated mRNA decay.
    
 0.836
dhx38
DEAH (Asp-Glu-Ala-His) box polypeptide 38.
    
 0.779
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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