Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
H2RNF6_TAKRULeucine zipper, putative tumor suppressor 1. (549 aa)    
Predicted Functional Partners:
LOC101076198
Unc-119 lipid binding chaperone.
    
   0.865
LOC101063149
Unc-119 lipid binding chaperone.
    
   0.865
LOC101075662
Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family.
    
   0.738
lzts2
Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family.
    
   0.738
ENSTRUP00000083198
Leucine zipper putative tumor suppressor 3.
    
   0.738
flad1
FAD synthase; Catalyzes the adenylation of flavin mononucleotide (FMN) to form flavin adenine dinucleotide (FAD) coenzyme. In the C-terminal section; belongs to the PAPS reductase family. FAD1 subfamily.
      
 0.520
LOC101063823
GMP_PDE_delta domain-containing protein.
    
   0.519
unc119b
Unc-119 homolog 1.
    
   0.519
sestd1
SEC14 and spectrin domains 1.
      
 0.519
sult4a1
Sulfotransferase; Belongs to the sulfotransferase 1 family.
      
 0.517
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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