STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
LOC101071062Sprouty related EVH1 domain containing 2a. (427 aa)    
Predicted Functional Partners:
psmd2
26S proteasome non-ATPase regulatory subunit 2; Component of the 26S proteasome, a multiprotein complex involved in the ATP-dependent degradation of ubiquitinated proteins. This complex plays a key role in the maintenance of protein homeostasis by removing misfolded or damaged proteins, which could impair cellular functions, and by removing proteins whose functions are no longer required. Therefore, the proteasome participates in numerous cellular processes, including cell cycle progression, apoptosis, or DNA damage repair; Belongs to the proteasome subunit S2 family.
   
 
 0.699
LOC101074386
Sequestosome 1.
    
   0.604
LOC101069736
Zgc:55558.
   
 0.584
hras
HRas proto-oncogene, GTPase a.
   
 0.584
kras
V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog.
   
 0.584
CSDE1
Cold shock domain containing E1, RNA-binding.
   
 0.584
ofd1
OFD1 centriole and centriolar satellite protein.
    
 
 0.568
nek2
NIMA-related kinase 2.
    
 0.561
rin2
Si:ch211-85n16.4.
      
 0.560
fgfrl1
Fibroblast growth factor receptor like 1a.
     
 0.553
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.