Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
wwc1WW and C2 domain containing 1. (1156 aa)    
Predicted Functional Partners:
lats1
Large tumor suppressor kinase 1.
    
 0.624
lats2
Large tumor suppressor kinase 2.
    
 0.624
tmem9
Putative protein 2.
    
 
 0.623
tmem9b
TMEM9 domain family, member B.
    
 
 0.623
LOC101077791
Uncharacterized protein.
      
 0.553
exosc10
Exosome component 10.
     
 0.534
ostm1
Osteoclastogenesis associated transmembrane protein 1.
    
 0.530
fbf1
Uncharacterized protein.
      
 0.511
DBI
Diazepam binding inhibitor (GABA receptor modulator, acyl-CoA binding protein).
      
 0.507
LOC101075777
Malate synthase-like.
      
 0.444
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (50%) [HD]