Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
rnf170Ring finger protein 170. (261 aa)    
Predicted Functional Partners:
tmub1
Transmembrane and ubiquitin-like domain containing 1.
    
 
 0.947
LOC101067994
ER lipid raft associated 1.
    
 
 0.871
LOC101072418
Cholesterol 25-hydroxylase like 3.
    
 
 0.871
C17h6orf120
Zgc:77929.
      
 0.748
blm
BLM RecQ like helicase.
    
 
 0.674
LOC101066197
Uncharacterized protein.
      
 0.654
ppm1e
Protein phosphatase, Mg2+/Mn2+ dependent, 1E.
      
 0.647
tmem259
Transmembrane protein 259.
      
 0.646
cgrrf1
Cell growth regulator with ring finger domain 1.
      
 0.646
tor2a
Torsin family 2, member A.
      
 0.618
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: low (18%) [HD]