STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
MMEMembrane metalloendopeptidase. (772 aa)    
Predicted Functional Partners:
agt
Angiotensinogen; Belongs to the serpin family.
    
 0.844
plch1
Phosphoinositide phospholipase C.
      
 0.701
ide
Insulin-degrading enzyme; Belongs to the peptidase M16 family.
      
 0.697
edn1
Endothelin 1.
     
 0.654
gmps
Guanine monophosphate synthase.
   
  
 0.616
nppa
Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.
    
 
 0.587
plch2
Phospholipase C eta 2.
      
 0.572
prkx
Protein kinase X-linked; Belongs to the protein kinase superfamily.
      
 0.540
ace
Angiotensin-converting enzyme.
   
  
 0.529
prep
Prolyl endopeptidase.
   
  
 0.525
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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