nppb protein (Takifugu rubripes) - STRING interaction network

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nppb

Brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family. (275 aa)

Predicted Functional Partners:

nppa

0.990

npr3

0.971

LOC101072043

0.967

LOC101062907

0.967

ide

0.768

nppc

0.728

LOC101073658

0.691

LOC101074483

0.691

LOC101076108

0.691

cnp-3

0.642

Your Current Organism:

Takifugu rubripes

NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101062907	LOC101072043	ENSTRUP00000071616	ENSTRUP00000057947	Guanylate cyclase.	Guanylate cyclase.	0.901
LOC101062907	nppa	ENSTRUP00000071616	ENSTRUP00000088156	Guanylate cyclase.	Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.981
LOC101062907	nppb	ENSTRUP00000071616	ENSTRUP00000079039	Guanylate cyclase.	Brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.967
LOC101062907	nppc	ENSTRUP00000071616	ENSTRUP00000022021	Guanylate cyclase.	C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.	0.816
LOC101072043	LOC101062907	ENSTRUP00000057947	ENSTRUP00000071616	Guanylate cyclase.	Guanylate cyclase.	0.901
LOC101072043	nppa	ENSTRUP00000057947	ENSTRUP00000088156	Guanylate cyclase.	Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.981
LOC101072043	nppb	ENSTRUP00000057947	ENSTRUP00000079039	Guanylate cyclase.	Brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.967
LOC101072043	nppc	ENSTRUP00000057947	ENSTRUP00000022021	Guanylate cyclase.	C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.	0.816
LOC101073658	nppa	ENSTRUP00000020710	ENSTRUP00000088156	Guanylate cyclase.	Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.826
LOC101073658	nppb	ENSTRUP00000020710	ENSTRUP00000079039	Guanylate cyclase.	Brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.691
LOC101073658	nppc	ENSTRUP00000020710	ENSTRUP00000022021	Guanylate cyclase.	C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.	0.816
LOC101074483	nppa	ENSTRUP00000027478	ENSTRUP00000088156	Guanylate cyclase.	Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.826
LOC101074483	nppb	ENSTRUP00000027478	ENSTRUP00000079039	Guanylate cyclase.	Brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.691
LOC101074483	nppc	ENSTRUP00000027478	ENSTRUP00000022021	Guanylate cyclase.	C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.	0.982
LOC101076108	nppa	ENSTRUP00000085801	ENSTRUP00000088156	Si:ch211-215j19.12; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.826
LOC101076108	nppb	ENSTRUP00000085801	ENSTRUP00000079039	Si:ch211-215j19.12; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	Brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.691
LOC101076108	nppc	ENSTRUP00000085801	ENSTRUP00000022021	Si:ch211-215j19.12; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.	C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.	0.816
cnp-3	nppa	ENSTRUP00000009486	ENSTRUP00000088156	C-type natriuretic peptide 3; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.	Atrial natriuretic factor; Hormone playing a key role in cardiovascular homeostasis through regulation of natriuresis, diuresis, and vasodilation. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.454
cnp-3	nppb	ENSTRUP00000009486	ENSTRUP00000079039	C-type natriuretic peptide 3; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.	Brain natriuretic peptide; Cardiac hormone which may function as a paracrine antifibrotic factor in the heart. Also plays a key role in cardiovascular homeostasis through natriuresis, diuresis, vasorelaxation, and inhibition of renin and aldosterone secretion. Has a cGMP-stimulating activity (By similarity); Belongs to the natriuretic peptide family.	0.642
cnp-3	nppc	ENSTRUP00000009486	ENSTRUP00000022021	C-type natriuretic peptide 3; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.	C-type natriuretic peptide 4; Exhibits natriuretic and vasodepressant activity. Has cGMP- stimulating activity. May help to regulate body fluid homeostasis in a variety of aquatic environments; Belongs to the natriuretic peptide family.	0.658

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