Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
ibtkInhibitor of Bruton agammaglobulinemia tyrosine kinase. (1362 aa)    
Predicted Functional Partners:
cul3
Cullin 3a; Belongs to the cullin family.
   
 0.971
rpp25l
Ribonuclease P/MRP 25 subunit-like.
    
 
 0.939
dnajc17
DnaJ (Hsp40) homolog, subfamily C, member 17.
      
 0.891
H2V3I0_TAKRU
Alba domain-containing protein.
    
   0.788
cacul1
Cullin domain-containing protein; Belongs to the cullin family.
   
 0.773
irak1bp1
Interleukin-1 receptor-associated kinase 1 binding protein 1.
      
 0.730
LOC101069921
Amyloid beta precursor protein binding family A member 3.
      
 0.712
Ankrd9
Ankyrin repeat domain 9.
    
 0.708
LOC101077899
Zgc:112001.
    
 0.708
itk
Tyrosine-protein kinase.
   
 
 0.677
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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