Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
foxo3Forkhead box O3b. (659 aa)    
Predicted Functional Partners:
sirt1
Sirtuin 1.
    
 0.989
usp7
Ubiquitin specific peptidase 7 (herpes virus-associated); Belongs to the peptidase C19 family.
   
 0.977
AKT2
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.975
LOC101065438
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.975
LOC101073734
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.975
LOC101071975
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.975
akt1
Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.
    
 0.974
LOC101072871
Mothers against decapentaplegic homolog.
    
 0.960
stk11
Serine/threonine kinase 11; Belongs to the protein kinase superfamily.
    
 0.951
ikbkb
Inhibitor of nuclear factor kappa B kinase subunit beta.
    
 0.945
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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