Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ptpn23Protein tyrosine phosphatase, non-receptor type 23, a. (1891 aa)    
Predicted Functional Partners:
stam2
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 2.
   
 0.959
hgs
Hepatocyte growth factor-regulated tyrosine kinase substrate.
   
 0.917
stam
Signal transducing adaptor molecule (SH3 domain and ITAM motif) 1.
   
 0.828
grb2
Growth factor receptor-bound protein 2b.
   
 0.823
LOC101061204
Uncharacterized protein.
   
 0.823
ENSTRUP00000018134
GRB2 related adaptor protein 2a.
   
 0.789
LOC101063794
GRB2 related adaptor protein 2a.
   
 0.789
LOC101076389
F-BAR domain-containing protein.
   
 0.778
gas7
Growth arrest-specific 7a.
   
 0.778
LOC101078992
UEV domain-containing protein.
   
 0.749
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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