Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
LOC105418730Kelch-like family member 33. (463 aa)    
Predicted Functional Partners:
cct3
T-complex protein 1 subunit gamma.
    
   0.571
LOC115248454
RING-box protein 1.
    
 0.559
LOC101079814
Ring-box 1, E3 ubiquitin protein ligase.
    
 0.559
cct5
Chaperonin containing TCP1, subunit 5 (epsilon).
    
   0.544
cct8
Chaperonin containing TCP1, subunit 8 (theta).
    
   0.533
cul3
Cullin 3a; Belongs to the cullin family.
    
 0.528
cacul1
Cullin domain-containing protein; Belongs to the cullin family.
    
 0.522
cct7
T-complex protein 1 subunit eta; Molecular chaperone; assists the folding of proteins upon ATP hydrolysis. Known to play a role, in vitro, in the folding of actin and tubulin.
    
   0.518
Ccdc24
Uncharacterized protein.
      
 0.511
pik3r4
Phosphoinositide-3-kinase, regulatory subunit 4.
      
 0.501
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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