STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
plk3Serine/threonine-protein kinase PLK. (667 aa)    
Predicted Functional Partners:
espl1
Extra spindle pole bodies like 1, separase.
   
 0.991
cdc25b
Cell division cycle 25B.
   
 0.990
smc1a
Structural maintenance of chromosomes protein.
   
 0.987
plk4
Polo-like kinase 4 (Drosophila).
   
0.977
bora
Bora aurora kinase A activator.
   
 0.974
LOC101078750
RAD21 cohesin complex component like 1.
   
 0.969
rad21
RAD21 cohesin complex component a.
   
 0.969
smc3
Structural maintenance of chromosomes protein.
   
 0.958
ppp4c
Serine/threonine-protein phosphatase.
   
 0.957
mad2l1
MAD2 mitotic arrest deficient-like 1 (yeast).
   
 0.953
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
Server load: medium (52%) [HD]