STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
irf2Interferon regulatory factor. (396 aa)    
Predicted Functional Partners:
LOC101075171
Interferon regulatory factor.
  
0.800
irf2bp1
Interferon regulatory factor 2 binding protein 1.
   
 
 0.602
LOC101075252
IRF-2BP1_2 domain-containing protein.
   
 
 0.602
LOC101065615
Interferon regulatory factor 2 binding protein 2.
   
 
 0.602
LOC101078177
Proto-oncogene c-Fos; Nuclear phosphoprotein which forms a tight but non-covalently linked complex with the JUN/AP-1 transcription factor. FOS has a critical function in regulating the development of cells destined to form and maintain the skeleton. It is thought to have an important role in signal transduction, cell proliferation and differentiation (By similarity).
    
 
 0.595
LOC105417094
Interferon regulatory factor 2 binding protein 1.
   
 
 0.541
plk3
Serine/threonine-protein kinase PLK.
   
 0.535
irf7
Interferon regulatory factor 7.
   
  
 0.499
ENSTRUP00000005140
TANK-binding kinase 1.
   
 0.469
mdm2
MDM2 proto-oncogene.
    
 0.461
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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