Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
nr2e1Nuclear receptor subfamily 2, group E, member 1. (396 aa)    
Predicted Functional Partners:
atn1
Atrophin 1.
    
 0.783
LOC101074077
Arginine-glutamic acid dipeptide (RE) repeats b.
    
 0.783
rere
Arginine-glutamic acid dipeptide (RE) repeats a.
    
 0.783
kdm1a
Lysine-specific histone demethylase; Histone demethylase that demethylates both 'Lys-4' (H3K4me) and 'Lys-9' (H3K9me) of histone H3, thereby acting as a coactivator or a corepressor, depending on the context. Acts by oxidizing the substrate by FAD to generate the corresponding imine that is subsequently hydrolyzed. Acts as a corepressor by mediating demethylation of H3K4me, a specific tag for epigenetic transcriptional activation. Demethylates both mono- (H3K4me1) and di-methylated (H3K4me2) H3K4me; Belongs to the flavin monoamine oxidase family.
    
 0.706
LOC101076672
Neural retina leucine zipper.
   
 0.671
ncor2
Nuclear receptor corepressor 2.
    
 0.626
ncor1
Nuclear receptor corepressor 1.
    
 0.626
prpf31
PRP31 pre-mRNA processing factor 31 homolog (yeast).
    
 
 0.603
mcph1
Microcephalin 1.
    
 
 0.601
sobp
Sine oculis binding protein homolog (Drosophila) a.
      
 0.601
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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