Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
LOC101070353Lysyl oxidase a. (423 aa)    
Predicted Functional Partners:
tyr
Tyrosinase.
      
 0.606
ENSTRUP00000066035
Elastin-like isoform X1.
    
 0.556
znrf1
Zinc and ring finger 1.
      
 0.513
fbln5
Fibulin 5.
   
 
 0.468
tgfb3
Transforming growth factor beta; Belongs to the TGF-beta family.
   
 0.445
LOC115246761
Asporin.
   
 0.435
tgf-beta1
Transforming growth factor beta; Belongs to the TGF-beta family.
    
 0.426
LOC101079595
Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family.
    
 0.416
bgn
Biglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily.
   
 0.412
LOC115252418
Uncharacterized protein LOC115252418.
    
 0.412
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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