Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
frat2Glycogen synthase kinase binding protein. (170 aa)    
Predicted Functional Partners:
gsk3b
Glycogen synthase kinase 3 beta, genome duplicate b; Belongs to the protein kinase superfamily.
    
 0.987
dvl3
Dishevelled segment polarity protein 3a.
    
 0.911
dvl2
Dishevelled segment polarity protein 2.
    
 0.911
dvl1
Dishevelled segment polarity protein 1a.
    
 0.911
LOC101065819
Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily.
    
 0.874
LOC101062691
Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily.
    
 0.874
apc
APC regulator of WNT signaling pathway.
    
 0.770
LOC101062949
Adenomatous polyposis coli protein 2-like isoform X1.
    
 0.770
ctnnb1
Catenin (cadherin-associated protein), beta 1.
     
 0.699
csnk1a1
Casein kinase 1, alpha 1; Belongs to the protein kinase superfamily.
     
 0.658
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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