Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
RAB40CRAB40C, member RAS oncogene family. (286 aa)    
Predicted Functional Partners:
cul5
Cullin 5a; Belongs to the cullin family.
    
 
 0.809
rabggtb
Geranylgeranyl transferase type-2 subunit beta; Catalyzes the transfer of a geranylgeranyl moiety from geranylgeranyl diphosphate to both cysteines of proteins with the C- terminal sequence -XXCC, -XCXC and -CCXX.
   
 0.806
eloc
Elongin C paralog a; Belongs to the SKP1 family.
   
 
 0.799
LOC101070508
Elongin-B isoform X1.
    
 
 0.699
LOC101068670
Ubiquitin-like domain-containing protein.
    
 
 0.699
MTHFSD
Methenyltetrahydrofolate synthetase domain containing.
   
    0.682
rilpl2
Rab interacting lysosomal protein-like 2.
    
 
 0.645
chm
Rab proteins geranylgeranyltransferase component A; Substrate-binding subunit (component A) of the Rab geranylgeranyltransferase (GGTase) complex. Binds unprenylated Rab proteins and presents the substrate peptide to the catalytic component B. The component A is thought to be regenerated by transferring its prenylated Rab back to the donor membrane.
    
 0.634
psme3ip1
Family with sequence similarity 192 member A.
    
   0.624
wdr6
WD repeat domain 6.
   
    0.614
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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