Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Neighborhood
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[Homology]
Score
pus1Pseudouridine synthase 1. (422 aa)    
Predicted Functional Partners:
wdr4
tRNA (guanine-N(7)-)-methyltransferase non-catalytic subunit WDR4; Required for the formation of N(7)-methylguanine at position 46 (m7G46) in tRNA. In the complex, it is required to stabilize and induce conformational changes of the catalytic subunit. Belongs to the WD repeat TRM82 family.
   
 
 0.963
LOC101073954
Dyskeratosis congenita 1, dyskerin.
   
 0.938
Trub1
Uncharacterized protein.
   
 0.938
pus7
Pseudouridine synthase 7.
   
 
 0.884
wdr12
Ribosome biogenesis protein WDR12; Component of the PeBoW complex, which is required for maturation of 28S and 5.8S ribosomal RNAs and formation of the 60S ribosome.
   
 
 0.869
ENSTRUP00000086673
annotation not available
  
 
 0.849
trub2
TruB pseudouridine (psi) synthase family member 2.
   
 0.830
yars2
Tyrosine--tRNA ligase.
  
 
 0.803
ddx18
RNA helicase.
  
 
 0.798
pus7l
Pseudouridine synthase 7 like.
   
 
 0.779
Your Current Organism:
Takifugu rubripes
NCBI taxonomy Id: 31033
Other names: Fugu rubripes, Sphaeroides rubripes, T. rubripes, Tetraodon rubripes, tiger puffer, torafugu
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